Radiation Oncology - An Evidence-Based Approach (Springer, 2008).pdf

Radiation Oncology - An Evidence-Based Approach (Springer, 2008).pdf

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Radiation Oncology - An Evidence-Based Approach (Springer, 2008).pdf Contents I MEDICAL RADIOLOGY Radiation Oncology Editors: L.W. Brady, Philadelphia H.-P. Heilmann, Hamburg M. Molls, Munich C. Nieder, Bodø LuBrady-BOOK.indb I 13.08.2008 13:58:05 Contents III J. J. Lu · L. W. Brady (Eds.) Radiation Oncology An Evidence-Based Approach With Contributions by A. A. Abitbol · R. R. Allison · B. Amendola · M. F. Back · J. J. Beitler · M. Biagioli · E. B. Butler J. S. Butler · L. W. Brady · M. Chadha · A. Y. Chen · W-J. Chng · W. H. Choi · H. T. Chung J. S. Cooper · B. R. Donahue · S. Fu · H. A. Gay · I. C. Gibbs · S. C. Han · L. B. Harrison G. F. Hatoum · J. M. Herman · D. Hristov · K. Hu · B. J. Huth · A. J. Khan · F-M. Kong L. Kong · K. LaFave · E. M. Landau · K. M. Lee · N. Lee · Y. Li · J. J. Lu · A. M. Markoe V. K. Mehta · S. Mutyala · R. Ove · A. C. Paulino · T. M. Pawlik · J. A. Peñagarícano C. L. Perkins · V. Ratanatharathorn · S. G. Soltys · M. M. Spierer · C. Takita · B. S. Teh B-C. Wen · A. H. Wolfson · X. Wu · L. Xing · T. E. Yaeger · Q. Zhang · Z. Zhang Foreword by L.W. Brady · H.-P. Heilmann · M. Molls · C. Nieder Introduction by J. J. Lu and L.W. Brady With 150 Figures in 219 Separate Illustrations, 176 in Color and 147 Tables 123 LuBrady-BOOK.indb III 13.08.2008 13:58:09 IV Contents Jiade J. Lu, MD, MBA Associate Professor and Consultant Department of Radiation Oncology National University Cancer Institute of Singapore National University Health System National University of Singapore 5 Lower Kent Ridge Road Singapore 119074 Singapore and Distinguished Clinical Professor Department of Radiation Oncology Cancer Hospital of Fudan University 270 Dong An Road Shanghai 200232 P. R. China Medical Radiology · Diagnostic Imaging and Radiation Oncology Series Editors: A. L. Baert · L. W. Brady · H.-P. Heilmann · M. Knauth · M. Molls · C. Nieder Continuation of Handbuch der medizinischen Radiologie Encyclopedia of Medical Radiology ISBN 978-3-540-77384-9 e-ISBN 978-3-540-77385-6 DOI 10.1007 / 978-3-540-77385-6 Medical Radiology · Diagnostic Imaging and Radiation Oncology Library of Congress Control Number: 2008922317 2008, Springer-Verlag Berlin Heidelberg This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifi cally the rights of translation, reprinting, reuse of illustrations, recitations, broadcasting, reproduction on microfi lm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permit- ted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permis- sion for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. The use of general descriptive names, trademarks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application contained in this book. In every individual case the user must check such information by consulting the relevant literature. Cover-Design and Layout: PublishingServices Teichmann, 69256 Mauer, Germany Printed on acid-free paper – 21/3180xq 9 8 7 6 5 4 3 2 1 springer.com Luther W. Brady, MD Hylda Cohn/American Cancer Society Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor Drexel University, College of Medicine Broad & Vine Sts., Mail Stop 200 Philadelphia, PA 19102-1192 USA LuBrady-BOOK.indb IV 13.08.2008 13:58:09 Contents V Foreword For the past ten years there have been signifi cant scientifi c advances in biological sci- ences and healthcare. At the same time, there has been increased accountability and, in some instances, attempts to ration services as a mechanism to accomplish this. Although arbitrary clinical practice guidelines have been published, more rational bases to defi ne optimal healthcare should be based on the identifi cation of innovative approaches, outcome analysis in properly designed clinical trials, and careful assess- ment of current practice based on solid and creditable clinical research and evidence based decision making in medicine. The growth in basic and translational research data offers a guide to medical practice and is essential for the clinician to appraise and use published evidence for medical decisions. Evidence based medicine exemplifi es the effect of teaching clinicians to evaluate research data by methodologic standards and to critically appraise published evidence from both a scientifi c and sociocultural perspective. Physicians are trained to maintain high standards of critical conscious- ness in methodologic domains, but not necessarily in the broader historic sociocultural domains surrounding them. It is important for those practicing evidence based medicine to take full advantage of their encounters with patients, where the questions and answers that may arise can lead to providing the patient with the best available medical care. Appropriate and relevant clinical questions relate to the patient and the problem, to intervention, to a comparison intervention, and to outcome. The present volume is specifi cally aimed at the utilization of evidence based medi- cine in outcome from radiation oncology. It stands as a signifi cant and important stan- dard by which all programs in management can be judged. Philadelphia Luther W. Brady Hamburg Hans-Peter Heilmann Munich Michael Molls Bodø Carsten Nieder LuBrady-BOOK.indb V 13.08.2008 13:58:09 ...