Radiation Oncology - An Evidence-Based Approach (Springer, 2008).pdf
Radiation Oncology - An Evidence-Based Approach (Springer, 2008).pdf
Contents I
MEDICAL RADIOLOGY
Radiation Oncology
Editors:
L.W. Brady, Philadelphia
H.-P. Heilmann, Hamburg
M. Molls, Munich
C. Nieder, Bodø
LuBrady-BOOK.indb I 13.08.2008 13:58:05
Contents III
J. J. Lu · L. W. Brady (Eds.)
Radiation Oncology
An Evidence-Based Approach
With Contributions by
A. A. Abitbol · R. R. Allison · B. Amendola · M. F. Back · J. J. Beitler · M. Biagioli · E. B. Butler
J. S. Butler · L. W. Brady · M. Chadha · A. Y. Chen · W-J. Chng · W. H. Choi · H. T. Chung
J. S. Cooper · B. R. Donahue · S. Fu · H. A. Gay · I. C. Gibbs · S. C. Han · L. B. Harrison
G. F. Hatoum · J. M. Herman · D. Hristov · K. Hu · B. J. Huth · A. J. Khan · F-M. Kong
L. Kong · K. LaFave · E. M. Landau · K. M. Lee · N. Lee · Y. Li · J. J. Lu · A. M. Markoe
V. K. Mehta · S. Mutyala · R. Ove · A. C. Paulino · T. M. Pawlik · J. A. Peñagarícano
C. L. Perkins · V. Ratanatharathorn · S. G. Soltys · M. M. Spierer · C. Takita · B. S. Teh
B-C. Wen · A. H. Wolfson · X. Wu · L. Xing · T. E. Yaeger · Q. Zhang · Z. Zhang
Foreword by
L.W. Brady · H.-P. Heilmann · M. Molls · C. Nieder
Introduction by J. J. Lu and L.W. Brady
With 150 Figures in 219 Separate Illustrations, 176 in Color and 147 Tables
123
LuBrady-BOOK.indb III 13.08.2008 13:58:09
IV Contents
Jiade J. Lu, MD, MBA
Associate Professor and Consultant
Department of Radiation Oncology
National University Cancer Institute of Singapore
National University Health System
National University of Singapore
5 Lower Kent Ridge Road
Singapore 119074
Singapore
and
Distinguished Clinical Professor
Department of Radiation Oncology
Cancer Hospital of Fudan University
270 Dong An Road
Shanghai 200232
P. R. China
Medical Radiology · Diagnostic Imaging and Radiation Oncology
Series Editors:
A. L. Baert · L. W. Brady · H.-P. Heilmann · M. Knauth · M. Molls · C. Nieder
Continuation of Handbuch der medizinischen Radiologie
Encyclopedia of Medical Radiology
ISBN 978-3-540-77384-9 e-ISBN 978-3-540-77385-6
DOI 10.1007 / 978-3-540-77385-6
Medical Radiology · Diagnostic Imaging and Radiation Oncology
Library of Congress Control Number: 2008922317
2008, Springer-Verlag Berlin Heidelberg
This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned,
specifi cally the rights of translation, reprinting, reuse of illustrations, recitations, broadcasting, reproduction on
microfi lm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permit-
ted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permis-
sion for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German
Copyright Law.
The use of general descriptive names, trademarks, etc. in this publication does not imply, even in the absence of a
specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free
for general use.
Product liability: The publishers cannot guarantee the accuracy of any information about dosage and application
contained in this book. In every individual case the user must check such information by consulting the relevant
literature.
Cover-Design and Layout: PublishingServices Teichmann, 69256 Mauer, Germany
Printed on acid-free paper – 21/3180xq
9 8 7 6 5 4 3 2 1
springer.com
Luther W. Brady, MD
Hylda Cohn/American Cancer Society
Professor of Clinical Oncology, and
Professor, Department of Radiation Oncology
Distinguished University Professor
Drexel University, College of Medicine
Broad & Vine Sts., Mail Stop 200
Philadelphia, PA 19102-1192
USA
LuBrady-BOOK.indb IV 13.08.2008 13:58:09
Contents V
Foreword
For the past ten years there have been signifi cant scientifi c advances in biological sci-
ences and healthcare. At the same time, there has been increased accountability and,
in some instances, attempts to ration services as a mechanism to accomplish this.
Although arbitrary clinical practice guidelines have been published, more rational
bases to defi ne optimal healthcare should be based on the identifi cation of innovative
approaches, outcome analysis in properly designed clinical trials, and careful assess-
ment of current practice based on solid and creditable clinical research and evidence
based decision making in medicine. The growth in basic and translational research
data offers a guide to medical practice and is essential for the clinician to appraise and
use published evidence for medical decisions. Evidence based medicine exemplifi es
the effect of teaching clinicians to evaluate research data by methodologic standards
and to critically appraise published evidence from both a scientifi c and sociocultural
perspective. Physicians are trained to maintain high standards of critical conscious-
ness in methodologic domains, but not necessarily in the broader historic sociocultural
domains surrounding them.
It is important for those practicing evidence based medicine to take full advantage
of their encounters with patients, where the questions and answers that may arise can
lead to providing the patient with the best available medical care. Appropriate and
relevant clinical questions relate to the patient and the problem, to intervention, to a
comparison intervention, and to outcome.
The present volume is specifi cally aimed at the utilization of evidence based medi-
cine in outcome from radiation oncology. It stands as a signifi cant and important stan-
dard by which all programs in management can be judged.
Philadelphia Luther W. Brady
Hamburg Hans-Peter Heilmann
Munich Michael Molls
Bodø Carsten Nieder
LuBrady-BOOK.indb V 13.08.2008 13:58:09
...