Springer Pet Ct In Clinical Practice 2007.pdf
Springer Pet Ct In Clinical Practice 2007.pdf
PET/CT in
Clinical Practice
PET/CT in
Clinical Practice
T.B. Lynch
With Contributions by:
James Clarke
Gary Cook
Simon Hughes
Mark Love
Chris Marshall
Stephen Vallely
Lorraine Wilson
Sandra Woods
T.B. Lynch, MB, BSc, MSc, MRCP, FRCR
Senior Lecturer
Department of Medicine
Queen’s University
Belfast
and
Lead Nuclear Medicine Physician and Consultant Radiologist
Nuclear Medicine and Radiology Department
The Northern Ireland Cancer Centre
Belfast
UK
British Library Cataloguing in Publication Data
Lynch, T. B.
PET/CT in clinical practice
1. Cancer—Tomography 2. Computerized axial tomography
3. Tomography, Emission
I. Title
616.9′940757
ISBN-13: 9781846284304
ISBN-10: 1846284309
Library of Congress Control Number: 2006927787
ISBN-10: 1-84628-430-9 eISBN-10: 1-84628-504-6
ISBN-13: 978-1-84628-430-4 eISBN-13: 978-1-84628-504-2
Printed on acid-free paper.
© Springer-Verlag London Limited 2007
Apart from any fair dealing for the purposes of research or private study, or criti-
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relevant laws and regulations and therefore free for general use.
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drug dosage and application thereof contained in this book. In every individual case
the respective user must check its accuracy by consulting other pharmaceutical
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Preface
The combination of functional metabolic information and
anatomical data has been available since 2001, when the com-
bined PET/CT scanner was introduced. This technology has had
a significant impact on many medical disciplines, including car-
diology and neurology, but undoubtedly the greatest impact has
been in the field of oncological imaging. It is the ability of
PET/CT to accurately identify the anatomical location of abnor-
mal metabolic activity that has revolutionized the detection and
staging of many tumors.
With this in mind, this small book has been written. The focus
is on the role of PET/CT in cancers of the lung, esophagus, colon,
and head and neck. The text also considers the impact of PET/CT
on lymphoma, melanoma, and cancers of the reproductive
system.
Each chapter outlines the relevant staging system and illus-
trates how PET/CT can best be deployed in tumor evaluation. A
large number of PET and PET/CT images are included in each
cancer type, with illustrative case studies used to aid teaching
points. The presentation is basic, with many representative
images of each cancer type, as well as a comprehensive review
of normal PET/CT findings and commonly seen variants (Chapter
9). Chapter 1 provides a general introduction to cellular biology
and Chapter 10 provides a brief overview of the physics involved
in PET/CT.
This book does not consider the whole range of positron emit-
ters available but focuses only on the role of F-18 fluoro-
deoxyglucose (FDG). The emphasis throughout has been to
create an easy-to-read, accessible text, suitable for anyone inter-
ested in an introduction to PET/CT. The author hopes this book
will provide a useful introduction to this fascinating, rapidly
evolving and hugely influential area of medical imaging.
I would like to sincerely thank the Springer staff for its
significant input in the preparation of this book, in particular
...