2010_胰腺癌.pdf
2010_胰腺癌.pdf
Copyright © National Comprehensive Cancer Network 2010. All rights reserved. “NCCN”, the NCCN logo, and “National Comprehensive Cancer Network” are
registered trademarks of the National Comprehensive Cancer Network.
The Chinese edition of NCCN Clinical Practice Guidelines in Oncology-Pancreatic Cancer Guideline 2010 is the Chinese adapted version of NCCN Clinical Practice
Guidelines in Oncology-Pancreatic Cancer Guideline, V.1.2009 as permitted and endorsed by NCCN. It is the collaborative outcome of the National Comprehensive
Cancer Network and Chinese key opinion leaders of the field.
The original guideline and Chinese edition are both available at: http://www.nccn.org. To view the most recent and complete version of the guideline, go online to
www.nccn.org. These Guidelines and illustrations herein may not be reproduced in any form for any purpose without the express written permission of the NCCN.
These Guidelines are a work in progress that will be refined as often as new significant data becomes available. The NCCN Guidelines are a statement of consensus
of its authors regarding their views of currently accepted approaches to treatment. Any clinician seeking to apply or consult any NCCN guideline is expected to use
independent medical judgment in the context of individual clinical circumstance to determine any patient's care or treatment. The National Comprehensive Cancer
Network makes no warranties of any kind whatsoever regarding their content, use or application and disclaims any responsibility for their application or use in any way.
This publication should not be used for commercial purpose. It is provided for free to Chinese medical professions with the support of the unrestrictive educational
grant of Eli Lilly and Company which exerts no influence to the formation of the Chinese edition of NCCN Clinical Practice Guidelines in Oncology-Pancreatic Cancer
Guideline 2010.
肿瘤学临床实践指南(中国版)
2010年 第一版 胰腺癌NCCN ®
© National Comprehensive Cancer Network, Inc. All rights reserved. These guidelines and this illustration may not be reproduced in any form without the express written permission of NCCN.
The Chinese edition 2010 is the collaborative outcome of the National Comprehensive Cancer Network and Chinese key opinion leaders of the field. Translated and adapted with permission and endorsement from the National Comprehensive
Cancer Network. To view the most recent and complete version of this or any other guideline, visit www.nccn.org.
* Margaret Tempero, MD/Chair †‡
UCSF Comprehensive Cancer Center
J. Pablo Arnoletti, MD ¶
University of Alabama at Birmingham
Comprehensive Cancer Center
Stephen Behrman, MD ¶
St. Jude Children's Research Hospital/
University of Tennessee Cancer Institute
Edgar Ben-Josef, MD §
University of Michigan Comprehensive
Cancer Center
Al B. Benson, III, MD †
Robert H. Lurie Comprehensive Cancer
Center of Northwestern University
Jordan D. Berlin, MD †
Vanderbilt-INgram Cancer Center
Pankaj Bhargava, MD †Σ
Dana-Farber/ Brigham and Women’s
Cancer Center | Massachusetts General
Hospital Cancer Center
John L. Cameron, MD ¶
The Sidney Kimmel Comprehensive
Cancer Center at Johns Hopkins
Ephraim S. Casper, MD †
Memorial Sloan-Kettering Cancer Center
Steven J. Cohen, MD †
Fox Chase Cancer Center
NCCN胰腺癌专家组成员
Michelle Duff, PhD ¥
Pancreatic Cancer Action Network
(PanCAN)
Joshua D.I. Ellenhorn, MD ¶
City of Hope
William G. Hawkins, MD ¶
Siteman Cancer Center at Barnes-Jewish
Hospital and Washington University
School of Medicine
Lisa Hazard, MD §
Huntsman Cancer Institute at the
University of Utah
John P. Hoffman, MD ¶
Fox Chase Cancer Center
Boris Kuvshinoff, MD ¶
Roswell Park Cancer Institute
Mokenge P. Malafa, MD ¶
H. Lee Moffitt Cancer Center and
Research Institute at the University of
South Florida
Peter Muscarella II, MD ¤ ¶
Arthur G. James Cancer Hospital &
Richard J. Solove Research Institute at
The Ohio State University
Eric K. Nakakura, MD ¶
UCSF Comprehensive Cancer Center
Aaron R. Sasson, MD ¶
UNMC Eppley Cancer Center at The
Nebraska Medical Center
Mark Talamonti, MD ¶
Robert H. Lurie Comprehensive Cancer
Center of Northwestern University
Sarah P. Thayer, MD, PhD ¤
Dana-Farber/Brigham and Women’s Cancer
Center Massachusetts General Hospital
Cancer Center
Douglas S. Tyler, MD ¶
Duke Comprehensive Cancer Center
Robert S. Warren, MD ¶
UCSF Comprehensive Cancer Center
Samuel Whiting, MD, PhD
Fred Hutchinson Cancer Research
Center/Seattle Cancer Care Alliance
Christopher Willett, MD §
Dana-Farber/ Brigham and Women’s
Cancer Center Massachusetts General
Hospital Cancer Center
Robert A. Wolff, MD †
The University of Texas M. D. Anderson
Cancer Center
¤ 胃肠科
¶ 外科/肿瘤外科
§ 放射科/肿瘤放射科
† 肿瘤内科
‡ 血液科/血液肿瘤科
Σ 药理科
≠ 病理科
¥ 患者支持
* 编委会成员
NCCN ®胰腺癌 肿瘤学临床实践指南(中国版)2010年 第一版
© National Comprehensive Cancer Network, Inc. All rights reserved. These guidelines and this illustration may not be reproduced in any form without the express written permission of NCCN.
The Chinese edition 2010 is the collaborative outcome of the National Comprehensive Cancer Network and Chinese key opinion leaders of the field. Translated and adapted with permission and endorsement from the National Comprehensive
Cancer Network. To view the most recent and complete version of this or any other guideline, visit www.nccn.org.
NCCN特别鸣谢
NCCN指南中国版专家组
召集人：
孙 燕
中国医学科学院北京协和医学院
肿瘤医院
NCCN代表：
Al B. Benson, III, MD
Robert H. Lurie Comprehensive
Cancer Center of Northwestern
University
NCCN胰腺癌临床实践指南（中国版）专家组
执行组长及撰稿执笔人：
赵玉沛
中国医学科学院北京协和医学院北京协和医院
成员：
钟守先
中国医学科学院北京协和医学院北京协和医院
张太平
中国医学科学院北京协和医学院北京协和医院
徐瑞华
中山大学附属肿瘤医院
徐建明
中国人民解放军三○七医院
王杰军
中国人民解放军第二军医大学长征医院
王春友
华中科技大学同济医学院附属协和医院
王成锋
中国医学科学院北京协和医学院肿瘤医院
沈 琳
北京大学临床肿瘤学院、北京肿瘤医院
潘宏铭
浙江大学医学院附属邵逸夫医院
倪泉兴
复旦大学附属肿瘤医院
苗 毅
江苏省人民医院
梁力健
中山大学附属第一医院
梁 军
青岛大学医学院附属医院
李 进
复旦大学附属肿瘤医院
黄 镜
中国医学科学院北京协和医学院肿瘤医院
陈 杰
中国医学科学院北京协和医学院北京协和医院
别 平
重庆第三军医大学西南医院
白 莉（撰稿助理人）
中国人民解放军总医院（三○一医院）
执行组长：
赵 平
中国医学科学院北京协和医学院肿瘤医院
秦叔逵
中国人民解放军第八一医院
余子豪
中国医学科学院北京协和医学院肿瘤医院
肿瘤学临床实践指南(中国版)
2010年 第一版 胰腺癌NCCN ®
© National Comprehensive Cancer Network, Inc. All rights reserved. These guidelines and this illustration may not be reproduced in any form without the express written permission of NCCN.
The Chinese edition 2010 is the collaborative outcome of the National Comprehensive Cancer Network and Chinese key opinion leaders of the field. Translated and adapted with permission and endorsement from the National Comprehensive
Cancer Network. To view the most recent and complete version of this or any other guideline, visit www.nccn.org.
NCCN胰腺癌专家组成员
NCCN特别鸣谢
临床表现和检查（PANC-1）
无转移性疾病（PANC-2）
肿瘤可切除，无黄疸（PANC-3）
肿瘤有可能切除，无黄疸（PANC-4）
肿瘤局部晚期，不可切除，无黄疸，无远处转移（PANC-7）
肿瘤可切除，有黄疸，无远处转移（PANC-8）
肿瘤有可能切除，有黄疸，无远处转移（PANC-9）
肿瘤局部晚期，不可切除，有黄疸（PANC-11）
肿瘤无法切除，有黄疸，确诊为腺癌（PANC-12）
切除后复发：治疗（PANC-13）
诊断和分期原则（PANC-A）
肿瘤可切除的判定标准（PANC-B）
放射治疗原则（PANC-C）
化疗原则（PANC-D）
姑息和支持治疗原则（PANC-E）
讨论
参考文献
目 录
临床试验：NCCN认为任何肿瘤患者都可以在临床试验中得到最佳
处理，因此特别鼓励肿瘤患者参加临床试验研究。
NCCN对证据和共识的分类：
除非特别指出，NCCN对所有建议均达成2A类共识。
见NCCN对证据和共识的分类
声明：
本指南中标注“※”处为中国专家根据国内实际情况进行明显改动或
补充之处，内容有别于英文版，参考时请注意。
这些指南是作者们对目前认可的治疗方法所达成的共识，希望参考或应用这些指南的临床医师根据个人具体的临床情况做出独立的医疗判断，以决定患者所需的护理和治疗。对于任何有关指南的内容、使用或应用，NCCN不做任何
评论和担保，对指南任何方式的应用或使用，NCCN不承担任何责任。
这些指南的版权归NCCN所有。未经NCCN书面允许，这些指南及说明不得以任何形式复制。©2010。
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